(Z)-Rilpivirine, CAS 500287-94-5

Product Description: (Z)-Rilpivirine ((Z)-R278474) is the (Z)-isomer of Rilpivirine (HY-10574). Rilpivirine is an effective and selective diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). It exhibits potent antiviral activity against both wild-type HIV (EC50 = 0.4 nM) and mutant strains (EC50 = 0.1-2.0 nM)[1].

Formula: C22H18N6

References: [1]Reilly SW, et al. Late-Stage Carbon Isotope Exchange of Aryl Nitriles through Ni-Catalyzed C-CN Bond Activation. J Am Chem Soc. 2021 Mar 31;143(12):4817-4823.

CAS Number: 500287-94-5

Molecular Weight: 366.42

Research Area: Infection

Target: Drug Isomer;HIV;Reverse Transcriptase

• SKU: MEXHY-167642-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-167642-0
• Package Unit: Get quote
• Quantity Unit: STK