Zoniporide (hydrochloride hydrate) (Standard), CAS 863406-85-3

Product Description: Zoniporide (hydrochloride hydrate) (Standard) is the analytical standard of Zoniporide (hydrochloride hydrate). This product is intended for research and analytical applications. Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM)[1][2].

Formula: C17H19ClN6O2

References: [1]Tracey WR, et al. Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1). Cardiovasc Drug Rev. 2003 Spring;21(1):17-32./[2]Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11(6):803-7.

CAS Number: 863406-85-3

Molecular Weight: 374.82

Research Area: Cardiovascular Disease

Target: Na+/H+ Exchanger (NHE);Reference Standards

• SKU: MEXHY-105064DR-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-105064DR-0
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• Quantity Unit: STK