A2AAR/hMAO-B-IN-1, CAS 1439488-21-7

Product Description: A2AAR/hMAO-B-IN-1 (compoudn 17) is a non-xanthine dual-target inhibitor targeting the A2A adenosine receptor (A2AAR) (IC50: 34.9 nM) andMAO-B (Ki: 39.5 nM, human). A2AAR/hMAO-B-IN-1 inhibits A2AAR-induced cAMP accumulation and exhibits competitive, reversible inhibition of MAO-B. A2AAR/hMAO-B-IN-1 can be used in the study of neurodegenerative diseases such as Parkinson's disease (PD)[1].

Applications: Neuroscience-Neuromodulation

Formula: C18H16N2O2S

References: [1]Stössel A, et al. Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones. J Med Chem. 2013 Jun 13;56(11):4580-96.

CAS Number: 1439488-21-7

Molecular Weight: 324.40

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Adenosine Receptor;Monoamine Oxidase

• SKU: MEXHY-120826-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120826-5
• Package Unit: 5 mg
• Quantity Unit: STK