Product Description: Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C18H29ClN2O4
References: [1]Piquette-Miller, M. and F. Jamali, Pharmacokinetics and multiple peaking of acebutolol enantiomers in rats. Biopharm Drug Dispos, 1997. 18(6): p. 543-56./[2]Mostafavi, S., R. Lewanczuk, and R. Foster, Influence of acebutolol and metoprolol on cardiac output and regional blood flow in rats. Biopharm Drug Dispos, 2000. 21(4): p. 121-8./[3]Bristow MR, et al. Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology. Circ Res. 2011 Oct 28;109(10):1176-94.
CAS Number: 34381-68-5
Molecular Weight: 372.89
Compound Purity: 99.97
Research Area: Cardiovascular Disease; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : ≥ 50 mg/mL
Target: Adrenergic Receptor