Product Description: AG-041R is a potent and selective CCK2 Receptor/Gastrin antagonist. AG-041R inhibits gastrin-evoked secretion of pancreastatin with an IC50 of 2.2 nM. AG-041R inhibits cell growth of Mastomys ECL carcinoid tumor cells[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C31H36N4O5
References: [1]Ding XQ, et al. Evaluation of three novel cholecystokinin-B/gastrin receptor antagonists: a study of their effects on rat stomach enterochromaffin-like cell activity. Pharmacol Toxicol. 1997 Nov;81(5):232-7./[2]Lindström, E., et al. Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells. Br. J. Pharmacol. 127(2), 530-536 (1999).
CAS Number: 159883-95-1
Molecular Weight: 544.64
Research Area: Cancer; Endocrinology
Solubility: 10 mM in DMSO
Target: Cholecystokinin Receptor
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