Product Description: AH 11110A is an α1B-adrenoceptor antagonist, but it can't effectively distinguish between the different subtypes of alpha(1) adrenoceptors (A, B, and D), nor can it clearly differentiate between alpha(1) and alpha(2) adrenoceptors[1][2].
Formula: C21H27ClN2O2
References: [1]M Eltze, et al. Failure of AH11110A to functionally discriminate between alpha(1)-adrenoceptor subtypes A, B and D or between alpha(1)- and alpha(2)-adrenoceptors. Eur J Pharmacol. 2001 Mar;415(2-3):265-76./[2]Hua Zhang, et al. Different alpha-adrenoceptors mediate migration of vascular smooth muscle cells and adventitial fibroblasts in vitro. Am J Physiol Heart Circ Physiol. 2002 Jun;282(6):H2364-70.
CAS Number: 179388-65-9
Molecular Weight: 374.90
Research Area: Neurological Disease; Cardiovascular Disease
Target: Adrenergic Receptor
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