Product Description: Alniditan (Alnitidan) dihydrochloride is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK293 cells, respectively. Alniditan dihydrochloride has migraine-preventive effects[1][2].
Applications: COVID-19-immunoregulation
Formula: C17H28Cl2N4O
References: [1]Limmroth V, et al. Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery. Eur J Pharmacol. 1999 Oct 8;382(2):103-9./[2]Lesage AS, et al. Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. Br J Pharmacol. 1998 Apr;123(8):1655-65.
CAS Number: 155428-00-5
Molecular Weight: 375.34
Compound Purity: 99.70
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: 5-HT Receptor
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