Product Description: ALW-II-41-27 is a Eph family tyrosine kinase inhibitor with an IC50 of 11 nM for Eph2.
Applications: Cancer-Kinase/protease
Formula: C32H32F3N5O2S
References: [1]Choi, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters (2009), 19(15), 4467-4470./[2]Song W, et al. Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers. Oncogene. 2017 Jun 5.
CAS Number: 1186206-79-0
Molecular Weight: 607.69
Compound Purity: 99.70
Research Area: Cancer
Solubility: DMSO : ≥ 47 mg/mL
Target: Ephrin Receptor