Anticancer agent 271

Product Description: Anticancer agent 271 (compound 5C) has antiproliferative activity against lung (A549), colon (Caco-2) cancer cell lines, and human lung fibroblast (WI38) with an IC50 value of 9.18 μM on A549 cells. Anticancer agent 271 downregulates PI3K and mTOR gene expression that can be used for cancer research[1].

Applications: Cancer-Kinase/protease

Formula: C26H18F3N5O3

References: [1]Mohammed Salah Ayoup, et al. Investigating the Anticancer Activity of Novel 1,2,4-Oxadiazole-Linked 1,2,3-Triazole Moieties via EGFR/pI3K/mTOR Cascade Down-Regulation. Polycyclic Aromatic Compounds. 26 Feb 2025.

Molecular Weight: 505.45

Research Area: Cancer

Target: EGFR;mTOR;PI3K

• SKU: MEXHY-173367-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173367-0
• Package Unit: Get quote
• Quantity Unit: STK