Product Description: AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonist activity. AR ligand 40 exhibits antiproliferative effect on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells with EC50s of 7, 10, 12, 13, 15 and 39 μM[1].
Formula: C21H25N5
References: [1]Córdoba-Gómez LB, et al. Exploring Trisubstituted adenine derivatives as adenosine A1 receptor ligands with antagonist activity: Synthesis, biological evaluation and molecular modelling. Bioorg Chem. 2025 Jun 1;159:108395.
Molecular Weight: 347.46
Research Area: Cancer
Target: Adenosine Receptor