BMS-819881, CAS 1197420-05-5

Product Description: BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM. BMS-819881 also is selective and potent for CYP3A4 activity with an EC50 of 13 μM.

Applications: Metabolism-sugar/lipid metabolism

Formula: C24H21ClN2O4S

References: [1]Washburn WN, et al. Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate. J Med Chem. 2014 Sep 25;57(18):7509-22.

CAS Number: 1197420-05-5

Molecular Weight: 468.95

Compound Purity: 99.78

Research Area: Metabolic Disease; Endocrinology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Cytochrome P450;MCHR1 (GPR24)

• SKU: MEXHY-12433-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12433-10
• Package Unit: 10 mg
• Quantity Unit: STK