Product Description: CCR5-IN-1 (compound 3ad) is a selective allosteric CCR5 inhibitor with an IC50 of 1.09 μM. CCR5-IN-1 can be used in the study of cardiovascular, central nervous system, immune system, and infectious diseases[1].
Formula: C18H14Cl3N7O4S
References: [1]Billen M, et al. Discovery and exploration of disubstituted [1,2,5]oxadiazolo-[3,4-b]pyrazines as novel C-C chemokine receptor type 5 signaling inhibitors targeting the intracellular allosteric binding pocket. Eur J Med Chem. 2025 Jul 5;291:117600.
Molecular Weight: 530.77
Research Area: Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Target: CCR