Dirozalkib, CAS 1893419-37-8

Dirozalkib, CAS 1893419-37-8
SKU
MEXHY-172426-0
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MedChemExpress

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Product Description: Dirozalkib (Compound 4) is the inhibitor for ALK with an IC50 of 0.9 nM. Dirozalkib exhibits anti-proliferative activity in cancer cells NCI-H3122, Karpas-299 and NCI-H2228 with IC50s of 130.4, 0.71 and 15.11 nM, respectively. Dirozalkib exhibits good pharmacokinetics characteristics with an bioavailbility of 30%~50%[1].

Formula: C27H32ClN5O4S

References: [1]Wu Y, et al., Polycyclic anaplastic lymphoma kinase inhibitor. WO2016050171

CAS Number: 1893419-37-8

Molecular Weight: 558.09

Research Area: Cancer

Target: Anaplastic lymphoma kinase (ALK)
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SKU MEXHY-172426-0
Manufacturer MedChemExpress
Manufacturer SKU HY-172426-0
Package Unit Get quote
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