EGFR-IN-160, CAS 2172879-84-2

EGFR-IN-160, CAS 2172879-84-2
SKU
MEXHY-173619-0
Packaging Unit
Get quote
Manufacturer
MedChemExpress

Availability: loading...
Price is loading...
Product Description: EGFR-IN-160 is an EGFR inhibitor (IC50 values are 1.62, 0.49 and 0.98 μM for EGFRWT, EGFRT790M and EGFRL858R/T790M/C797S, respectively). EGFR-IN-160 induces G2/M and S phase arrest and apoptosis in NCI-H522 cells, and has anticancer activity. EGFR-IN-160 has antioxidant effects against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM)[1].

Formula: C15H12N2O4

References: [1]Pal R, et al. Design, Synthesis, and Molecular Profiling of Pyrimidine-Furan Derivatives Targeting EGFRWT, EGFRT790M, and EGFRL858R/T790M/C797S in NSCLC: In Vitro and In Silico Evaluation. Chem Biodivers. 2025 Apr 19:e202500549.

CAS Number: 2172879-84-2

Molecular Weight: 284.27

Research Area: Cancer

Target: EGFR
More Information
SKU MEXHY-173619-0
Manufacturer MedChemExpress
Manufacturer SKU HY-173619-0
Package Unit Get quote
Quantity Unit STK
Product information (PDF)
×
MSDS (PDF)
×