Product Description: EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].
Applications: Cancer-Kinase/protease
Formula: C28H33N7O2
References: [1]Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.
CAS Number: 1835666-87-9
Molecular Weight: 499.61
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: EGFR