EGFR-IN-99, CAS 2068806-31-3

Product Description: EGFR-IN-99 (compound 1a) is a potent EGFR and HER2 Exon 20 insertion mutant inhibitor. EGFR-IN-99 has excellent antiproliferative activity against DFCI127 cells, with an EC50 of 11.5 nM. EGFR-IN-99 can be used for the research of non-small cell lung cancer (NSCLC)[1].

Applications: Cancer-Kinase/protease

Formula: C25H22FN7O3

References: [1]Jang J,et al. Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor. Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11629-11633.

CAS Number: 2068806-31-3

Molecular Weight: 487.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-123766-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123766-5
• Package Unit: 5 mg
• Quantity Unit: STK