Product Description: Erbstatin, a EGFR kinase inhibitor, possesses antineoplastic effect[1][2].
Applications: Cancer-Kinase/protease
Formula: C9H9NO3
References: [1]Shigeki Kobayashi, et al. Diastereomer-specific effects of double-stranded peptides conjugated with -L-Tyr-L-Phe- or -L-Tyr-D-Phe- residues on tyrosine phosphorylation and inhibition of src(ts)NRK, A431, MCF-7, and DU145 cell growth. Chem Pharm Bull (Tokyo). 2007 Nov;55(11):1585-92./[2]M Toi, et al. Antineoplastic effect of erbstatin on human mammary and esophageal tumors in athymic nude mice. Eur J Cancer. 1990;26(6):722-4./[3]S Simizu, et al. Involvement of hydrogen peroxide production in erbstatin-induced apoptosis in human small cell lung carcinoma cells. Cancer Res. 1996 Nov 1;56(21):4978-82.
CAS Number: 100827-28-9
Molecular Weight: 179.17
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;EGFR
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