FAK-IN-26, CAS 2801785-12-4

Product Description: FAK-IN-26 is a BBB-penetrable Focal Adhesion Kinase (FAK) inhibitor (IC50: 0.87 nM). FAK-IN-26 significantly suppresses tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 has potent anti-cancer activity in A549 and SKOV-3 tumor mice models with tumor inhibition rates of 59.15 % and 57.9 %[1].

Applications: Cancer-Kinase/protease

Formula: C20H19BrFN5O2

References: [1] Li Y, et al. Discovery of potent focal adhesion kinase (FAK) inhibitor A8 with enhanced antitumor activity. Eur J Med Chem. 2025 Jul 5; 291:117593.

CAS Number: 2801785-12-4

Molecular Weight: 460.30

Research Area: Cancer

Target: FAK

• SKU: MEXHY-173515-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173515-0
• Package Unit: Get quote
• Quantity Unit: STK