FAK-IN-27

Product Description: FAK-IN-27 (compound 8A) is a potent and selective FAK inhibitor with an IC50 of 4.968 nM. FAK-IN-27 suppresses H1299 cells proliferation with an IC50 of 0.28 μM. FAK-IN-27 can be used in the study of NSCLC[1].

Formula: C32H28ClN5O6

References: [1]Lei M, et al. Design, synthesis and biological evaluation of coumarin-containing 2,4-diphenylpyrimidine derivatives as novel focal adhesion kinase inhibitors for treatment of non-small cell lung cancer. Bioorg Med Chem Lett. 2025 Aug 1;123:130240.

Molecular Weight: 614.05

Research Area: Cancer

Target: FAK

• SKU: MEXHY-173603-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173603-0
• Package Unit: Get quote
• Quantity Unit: STK