Product Description: GSK1331268 is a selective, orally active agonist for mGluR2 with a pEC50 of 6.9. GSK1331268 exhibits good blood-brain barrier penetration. GSK1331268 regulates glutamate signaling, and can be used in research of neurodegenerative and neuropsychiatric diseases[1].
Formula: C17H19ClN6
References: [1]D'Alessandro PL, et al., The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2. Bioorg Med Chem Lett. 2010 Jan 15;20(2):759-62.
CAS Number: 1207197-70-3
Molecular Weight: 342.83
Research Area: Neurological Disease
Target: mGluR