JAK3-IN-17

Product Description: JAK3-IN-17 is an orally active JAK3 inhibitor (IC50: 14.56 nM). JAK3-IN-17 inhibits the production of IL-2 and IL-6 in a DNCB-induced mouse atopic dermatitis model and exhibits anti-inflammatory activity[1].

Formula: C21H15FN4O

References: [1]Ren W, et al. Discovery of novel JAK3 inhibitors for the treatment of atopic dermatitis. Bioorg Med Chem Lett. 2025 Aug 1;123:130219.

Molecular Weight: 358.37

Research Area: Inflammation/Immunology

Target: JAK

• SKU: MEXHY-173601-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173601-0
• Package Unit: Get quote
• Quantity Unit: STK