Product Description: MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis[1].
Applications: COVID-19-immunoregulation
Formula: C111H184N30O35.xC2HF3O2
References: [1]Chen CH, et al., A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene. 2014 Jul 10;33(28):3696-706.
Molecular Weight: 2498.83 (free acid)
Compound Purity: 99.88
Research Area: Cancer; Inflammation/Immunology
Solubility: DMSO : 13.3 mg/mL (ultrasonic)
Target: MARCKS;PKC