Product Description: Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis[1].
Formula: C13H18ClN3
References: [1]Hante NK, et al. Effect of mono-guanidine-like derivatives on platelet aggregation and tumour cell induced platelet aggregation. RSC Med Chem. 2025 Jan 31;16(4):1695-1704.
CAS Number: 1029802-21-8
Molecular Weight: 251.76
Research Area: Cancer; Cardiovascular Disease
Target: 5-HT Receptor;Adrenergic Receptor;Histamine Receptor
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