PNU-282987, CAS 123464-89-1

Product Description: PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems[1].

Applications: Neuroscience-Neuromodulation

Formula: C14H18Cl2N2O

References: [1]Alice L Bodnar, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem

CAS Number: 123464-89-1

Molecular Weight: 301.21

Compound Purity: 99.93

Research Area: Neurological Disease

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 50 mg/mL (ultrasonic)

Target: 5-HT Receptor;nAChR

• SKU: MEXHY-12560A-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12560A-25
• Package Unit: 25 mg
• Quantity Unit: STK