Product Description: RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM[1].
Applications: Neuroscience-Neuromodulation
Formula: C45H72N14O10
References: [1] Iain J Clarke, et al. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology
CAS Number: 311309-27-0
Molecular Weight: 969.14
Compound Purity: 99.21
Research Area: Neurological Disease
Solubility: DMSO : ≥ 100 mg/mL/H2O : ≥ 50 mg/mL
Target: Neuropeptide Y Receptor