Product Description: S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4[1].
Applications: COVID-19-immunoregulation
Formula: C23H24N2O3S
References: [1]Bell M, et al. Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Med Chem Lett. 2019 Feb 14;10(3):341-347.
CAS Number: 2328109-05-1
Molecular Weight: 408.51
Compound Purity: 99.52
Research Area: Inflammation/Immunology
Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming)
Target: LPL Receptor