SOF-436, CAS 2224491-20-5

Product Description: SOF-436 is a KRAS inhibitor that inhibits SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and the binding of KRAS to the effector protein RAF. SOF-436 can be used in cancer research[1].

Formula: C15H13F2NO4S2

References: [1]Landgraf A, et al. Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation. ChemMedChem. 2025 Mar 18:e202400624.

CAS Number: 2224491-20-5

Molecular Weight: 373.39

Research Area: Cancer

Target: Ras

• SKU: MEXHY-173341-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173341-0
• Package Unit: Get quote
• Quantity Unit: STK