Product Description: TASP0277308 is a highly selective S1P1 antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice[1].
Applications: COVID-19-immunoregulation
Formula: C23H28Cl2N6O3S
References: [1]Fujii Y, et al. Amelioration of collagen-induced arthritis by a novel S1P1 antagonist with immunomodulatory activities. J Immunol. 2012 Jan 1;188(1):206-15.
CAS Number: 945725-50-8
Molecular Weight: 539.48
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: LPL Receptor