TYK2 ligand 2, CAS 2924460-80-8

Product Description: TYK2 ligand 2 is a TYK2 ligand for TYD-68 (HY-173357). TYD-68 is a highly efficient and selective CRBN-recruited TYK2 PROTAC degrader with a DC50 value of 0.42 nM. TYD-68 can be used in the study of psoriasis[1].

Formula: C24H20FN7O4

References: [1]Xiong S, et al. Discovery of a Highly Potent and Selective Tyrosine Kinase 2 (TYK2) Degrader with In Vivo Therapeutic Efficacy in a Murine Psoriasis Model. J Med Chem. 2025 Apr 10;68(7):7560-7578.

CAS Number: 2924460-80-8

Molecular Weight: 489.46

Research Area: Inflammation/Immunology

Target: JAK

• SKU: MEXHY-173359-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173359-0
• Package Unit: Get quote
• Quantity Unit: STK