VB-85247

Product Description: VB-85247 is a STING agonist. VB-85247 induces upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as maturation and activation of dendritic cells by activating the STING pathway. VB-85247 can achieve regression of intrabladder tumors and can be used in bladder cancer research[1].

Applications: COVID-19-immunoregulation

Formula: C18H18FN9Na2O8P2S2

References: [1]Prabagar MG, et al. STING Agonist VB-85247 Induces Durable Antitumor Immune Responses by Intravesical Administration in a Non-Muscle-Invasive Bladder Cancer. Cancer Res. 2025 Apr 3;85(7):1287-1296.

Molecular Weight: 679.45

Research Area: Cancer; Inflammation/Immunology

Target: CXCR;IFNAR;Interleukin Related;STING;TNF Receptor

• SKU: MEXHY-173404-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173404-0
• Package Unit: Get quote
• Quantity Unit: STK