Product Description: Zongertinib (BI 1810631) is a potent and selective HER2 and EGFR tyrosine kinase inhibitor with IC50 values of 13 nM and 579 nM, respectively. Zongertinib has antitumor activity and can be used in the study of multiple solid tumors[1][2][3].
Applications: Cancer-Kinase/protease
Formula: C29H29N9O2
References: [1]WHO Drug Informat ion - World Health Organization (WHO)./[2]Wilding Birgit, et al. Synthesis of diazino-pyrimidines as anticancer agents: World Intellectual Property Organization, WO2021213800. 2021-10-28./[3]Li S, et al. Emerging Targeted Therapies in Advanced Non-Small-Cell Lung Cancer. Cancers (Basel). 2023 May 24;15(11):2899.
CAS Number: 2728667-27-2
Molecular Weight: 535.60
Compound Purity: 99.74
Research Area: Cancer
Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Target: c-Met/HGFR
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