Sirpiglenastat, CAS 2079939-05-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-acetyl-L-tryptophyl-6-diazo-5-oxo-L-norleucine, 1-methylethyl ester

Purity: ≥95%

Formula Markup: C22H27N5O5

Formula Weight: 441.48048

CAS Number: 2079939-05-0

Notes: A prodrug form of 6-diazo-5-oxo-L-nor-leucine; decreases P493B lymphoma cell viability (EC50 = 10 µM); metabolized to DON in tumor tissues, but metabolized to an inactive metabolite in gastrointestinal tissues, in CES1-/- mice bearing EL4, MC-38, EO771, or 3LL tumors; reduces tumor size in EL4 tumor-bearing CES1-/- mice at 0.1, 0.3, and 1 mg/kg

• SKU: CAY41293-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41293-1
• Package Unit: 1 mg
• Quantity Unit: STK