A-1899, CAS 498577-46-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[(2,4-difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-[1,1'-biphenyl]-2-carboxamide

Purity: ≥95%

Formula Markup: C30H26F2N2O3

Formula Weight: 500.545806

CAS Number: 498577-46-1

Notes: A K2P3.1/TASK1 inhibitor (IC50 = 0.035 µM in Xenopus oocytes expressing the human channel); selective for K2P3.1/TASK1 over K2P5.1/TASK2, K2P9.1/TASK3, and K2P17.1/TASK4 (IC50s = 12, 0.318, and 8.1 µM, respectively) and a panel of 16 additional potassium channels at 0.1 µM; selectively increases ERP in the left atrium over the right atrium and does not affect ventricular repolarization in anesthetized pigs at 3 mg/kg; stimulates breathing and induces respiratory alkalosis in spontaneously breathing anesthetized rats at 25 mg/kg

• SKU: CAY43018-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43018-5
• Package Unit: 5 mg
• Quantity Unit: STK