Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (+)-?-[[[[6-bromo-3-methyl-2-(1-pyrrolidinyl)-4-quinolinyl]carbonyl]amino]methyl]-2-chloro-benzenebutanoic acid
Purity: ≥95%
Formula Markup: C26H27BrClN3O3
Formula Weight: 544.874
CAS Number: 2247517-53-7
Notes: An FP receptor antagonist (IC50 = 11 nM); selective for the FP receptor over EP1, EP2, EP3, and EP4 receptors (IC50s = >10, >10, >10, and >9.4 µM, respectively), as well as IP and DP receptors (IC50s = >10 µM for both); reduces lung Il-1β levels and fibrosis in a mouse model of silica-induced pulmonary fibrosis at 30 mg/kg