Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N,a,a-trimethyl-N-[4-(2-methylphenyl)-6-(4-morpholinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide
Purity: ≥98%
Formula Markup: C29H29F6N3O2
Formula Weight: 565.560419
CAS Number: 290296-68-3
Notes: An NK1 receptor antagonist (Ki = 1 nM); inhibits GR73632-induced foot tapping in gerbils (ID50 = 0.2 mg/kg); decreases hemangiogenesis and lymphangiogenesis but induces corneal opacity, stromal leukocyte infiltration, and corneal toxicity in a mouse model of corneal alkali burn when applied topically at 0.4 or 1.6 mg/ml for four days