Bz 423, CAS 216691-95-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 7-chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one

Purity: ≥98%

Formula Markup: C27H21ClN2O2

Formula Weight: 440.92062

CAS Number: 216691-95-1

Notes: An inhibitor of mitochondrial complex V; inhibits mitochondrial complex V in bovine heart mitochondria at 10 µM; induces apoptosis and mitochondrial cytochrome c release in Ramos B cell lymphoma cells; induces cell cycle arrest in the G1 phase in Ramos cells at 10 µM; induces ROS production and decreases B cells in mice spleen at 60 mg/kg; reduces total splenic T cells and Cd4+ T cells levels, kidney fibrosis, synovial cell proliferation, and cartilage and subchondral bone erosion in an MRL/Mpj-Fas Ipr mouse model of spontaneous SLE at 60 mg/kg every two days

• SKU: CAY42608-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42608-10
• Package Unit: 10 mg
• Quantity Unit: STK