CHMFL-FLT3-122, CAS 1839150-56-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone

Purity: ≥95%

Formula Markup: C26H29N7O2

Formula Weight: 471.565

CAS Number: 1839150-56-9

Notes: An inhibitor of FLT3 (IC50 = 40 nM); selective for FLT3 over BTK and C-Kit (IC50s = 421 and 559 nM, respectively) and a panel of 468 additional kinases at 1 µM; inhibits the growth of MV4-11, MOLM-13, and MOLM-14 AML cells (GI50s = 22, 21, and 42 nM, respectively); inhibits tumor growth in an MV4-11 mouse xenograft model at 50 mg/kg

• SKU: CAY43137-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43137-5
• Package Unit: 5 mg
• Quantity Unit: STK