CX-08005, CAS 1256341-22-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[[[2-(tetradecyloxy)phenyl]amino]carbonyl]-benzoic acid

Purity: ≥98%

Formula Markup: C28H39NO4

Formula Weight: 453.623

CAS Number: 1256341-22-6

Notes: A PTP1B inhibitor (IC50 = 0.781 µM); selective for PTP1B over SHP-1, DUSP3, and LAR at 10 µM but does inhibit TCPTP (IC50 = 0.475 µM); CX08005 (100 and 200 mg/kg) decreases blood glucose levels in a glucose tolerance test in a model of DIO; increases red blood cell velocity and central and interlobular veins shear rates and decreases rolling and adhering leukocyte numbers in a mouse model of DIO at 100 mg/kg; decreases hepatic and plasma triglyceride levels in a KKAy mouse model of diabetes at 50 mg/kg

• SKU: CAY42730-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42730-5
• Package Unit: 5 mg
• Quantity Unit: STK