Product Description: Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor[1][2][3][4].
Applications: Metabolism-sugar/lipid metabolism
Formula: C22H29FO5
References: [1]Grigoriadis AE, et al. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J Cell Biol. 1988 Jun;106(6):2139-51./[2]Tenenbaum HC, Heersche JN. Dexamethasone stimulates osteogenesis in chick periosteum in vitro. Endocrinology. 1985 Nov;117(5):2211-7./[3]Rickard DJ, et al. Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol. 1994 Jan;161(1):218-28./[4]Alliot-Licht B, et al. Dexamethasone stimulates differentiation of odontoblast-like cells in human dental pulp cultures. Cell Tissue Res. 2005 Sep;321(3):391-400.
CAS Number: 50-02-2
Molecular Weight: 392.46
Research Area: Cancer; Infection; Endocrinology; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: ADC Cytotoxin;Glucocorticoid Receptor
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