Product Description: DMOG (GMP) is the GMP level of DMOG (HY-15893). DMOG (GMP) is a HIF-1α stabilizer. DMOG (GMP) promotes the osteogenic, angiogenic, and chondrogenic differentiation of stem cells by stabilizing the expression of HIF-1α. DMOG (GMP) can enhance the osteogenic and angiogenic differentiation potential of stem cells, thereby improving bone regeneration in bone defects. DMOG (GMP) can be used in the research of bone defect repair, vascularized bone regeneration, and the treatment of bone-related diseases (such as osteoporosis and femoral head necrosis) [1].
Formula: C6H9NO5
References: [1]Dong Q, et al. Effect of Dimethyloxalylglycine on Stem Cells Osteogenic Differentiation and Bone Tissue Regeneration-A Systematic Review. Int J Mol Sci. 2024 Mar 30;25(7):3879.
CAS Number: 89464-63-1
Molecular Weight: 175.14
Research Area: Cardiovascular Disease
Target: HIF/HIF Prolyl-Hydroxylase
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