EOAI3402143, CAS 1699750-95-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2E-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-2-propenamide

Purity: ≥98%

Formula Markup: C25H28Cl2N4O3

Formula Weight: 503.424

CAS Number: 1699750-95-2

Notes: An inhibitor of USP9X, USP24, and USP5; inhibits the catalytic domain of USP9X (IC50 = 1.6 µM); inhibits USP9X, USP24, and USP5 in MM.1S multiple myeloma cells at 5 µM; inhibits the growth of vemurafenib-sensitive and -resistant A375 cells (IC50s = 1 µM); reduces tumor volume in MM.1S and A375 mouse xenograft models at 15 mg/kg

• SKU: CAY43117-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43117-10
• Package Unit: 10 mg
• Quantity Unit: STK