Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2-(2,4-dichlorophenoxy)-benzeneacetic acid
Purity: ≥95%
Formula Markup: C14H10Cl2O3
Formula Weight: 297.1
CAS Number: 34645-84-6
Notes: Fenclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 7 and 4 µM for COX-1 and COX-2, respectively).{69949,1286} It reduces paw volume in a rat model of adjuvant-induced polyarthritis when administered at doses of 3, 15, and 75 mg/kg and reverses yeast-induced motor impairments, a measure of nociception, in rats (ED50 = 54.3 mg/kg).{69949} Fenclofenac (20-180 mg/kg) reduces carrageenan-induced paw edema in rats. Formulations containing fenclofenac have previously been used in the treatment of rheumatoid arthritis.