Glutaminase-IN-1, CAS 2247127-79-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-selenadiazol-2-yl]-2-pyridineacetamide

Purity: ≥95%

Formula Markup: C26H24F3N7O3Se

Formula Weight: 618.469349

CAS Number: 2247127-79-1

Notes: An inhibitor of GLS1 (IC50 = 1 nM); selective for GLS1 over GDH (IC50 = >13 µM); inhibits the proliferation of A549, H22, Caki-1, and HCT116 cancer cells (IC50s = 0.017, 6.78, 0.019, and 0.009 µM, respectively); induces ROS production in A549 cells at 10 µM; decreases tumor weight in an HCT116 mouse xenograft model at 10 mg/kg

• SKU: CAY42339-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42339-1
• Package Unit: 1 mg
• Quantity Unit: STK