Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide
Purity: ≥98%
Formula Markup: C27H18F5N5O4S
Formula Weight: 603.5
CAS Number: 1402345-92-9
Notes: GSK-F1 is a PI4KIIIα inhibitor (IC50 = 5.01 nM).{68864} It is selective for PI4KIIIα over PI4Kβ, PI3Kα, PI3Kβ, PI3Kδ, and PI4Kγ (IC50s = 1,000, 2,512, 7,943, 2,512, and 2,512 nM, respectively). GSK-F1 inhibits the replication of hepatitis C virus (HCV) genotypes 1a, 1b, and 2a in a cell-based replicon assay (IC50s = 12.6, 2.51, and 12.6 nM, respectively).