Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 3-oxo-olean-18-en-28-oic acid
Purity: ≥98%
Formula Markup: C30H46O3
Formula Weight: 454.7
CAS Number: 6713-27-5
Notes: A triterpenoid with diverse biological activities; inhibits α-glucosidase and α-amylase (IC50s = 10.57 and 20.08 µg/ml, respectively); inhibits the replication of HIV-1 in H9 T cells (EC50 = <0.1 µg/ml); decreases intestinal macrophage infiltration and the levels of Tnf-α, Il-6, and Il-1β in a mouse model of DSS-induced chronic colitis; inhibits TPA-induced ear edema in mice (ID50 = 379 nmol/ear); reduces the number of tumors per mouse and the percentage of mice with tumors in a two-stage mouse skin model of tumor formation initiated and promoted by DMBA and TPA, respectively