Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N,N'-1,4-butanediylbis[3-(4-hydroxy-3-methoxyphenyl)-2-propenamide
Purity: ≥95%
Formula Markup: C24H28N2O6
Formula Weight: 440.5
CAS Number: 42369-86-8
Notes: N,N′-Diferuloylputrescine is a polyamine that has been found in Z. mays and has diverse biological activities.{72451,72452,72453} It scavenges DPPH (Item No. 14805), superoxide, and hydroxyl radicals in cell-free assays (IC50s = 38.5, 291.6, and 351.9 µM, respectively).{72451} N,N′-Diferuloylputrescine inhibits tyrosinase (IC50 = 291.3 µM for the mushroom enzyme) and forskolin-induced pigmentation in B16/F10 melanoma cells when used at a concentration of 50 µg/ml.{72451,72452} It inhibits LPS-induced increases in nitric oxide (NO) and inducible nitric oxide synthase (iNOS) levels, as well as NF-κB activity, in RAW 264.7 macrophages when used at a concentration of 50 µM.{72453}
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