NPD4928, CAS 956965-61-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[(9,10-dihydro-3,4,8,8-tetramethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-5-yl)oxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-acetamide

Purity: ≥98%

Formula Markup: C29H32N2O6

Formula Weight: 504.57426

CAS Number: 956965-61-0

Notes: An FSP1 inhibitor and ferroptosis enhancer; binds to FSP1 and inhibits its activity in a cell-free NADH consumption assay; synergistically enhances RSL3-induced cytotoxicity in PANC-1 prostate cancer cells at 3 µM; induces cytotoxicity in PC3, MKN74, DU145, MIA PaCa-2, and A549 cells (IC50s = 95-155 nM, respectively) but not BxPC-3 or RPMI-8226 cells (IC50s = >30 µM for both) in combination with RSL3

• SKU: CAY36598-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36598-1
• Package Unit: 1 mg
• Quantity Unit: STK