NVP-LCQ195, CAS 902156-99-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[(2,6-dichlorobenzoyl)amino]-N-[1-(methylsulfonyl)-4-piperidinyl]-1H-pyrazole-3-carboxamide

Purity: ≥98%

Formula Markup: C17H19Cl2N5O4S

Formula Weight: 460.33

CAS Number: 902156-99-4

Notes: An inhibitor of CDKs; selectively inhibits Cdk5/p25, Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin A, and Cdk2/cyclin E complexes (IC50s = 1, 1, 2, 2, and 5 nM, respectively) over Cdk9/cyclin T1, Cdk3/cyclin E, Cdk6/cyclin D3, and Cdk7/cyclin H complexes (IC50s = 15, 42, 187, and 3,564 nM, respectively); decreases viability in a panel of 25 multiple myeloma cells (EC50s = 0.761-2.81 µM); induces cell cycle arrest at the G0 phase and apoptosis in MM.1S cells at 2 µM

• SKU: CAY42728-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42728-50
• Package Unit: 50 mg
• Quantity Unit: STK