NX-1607 (GMP), CAS 2573775-59-2

Product Description: NX-1607 (Cbl-b-IN-3) (GMP) is a GMP-grade NX-1607 (HY-141432). GMP-grade small molecules can be used as adjuvant agents in cell therapy. NX-1607 (GMP) enhances antigen recall, reduces T cell exhaustion and increases cytokine production. NX-1607 is an inhibitor of Cbl-b (an E3 enzyme)[1].

Formula: C30H34F3N5O

References: [1]Sharp A, et al. PB2099: A FIRST-IN-HUMAN PHASE 1 TRIAL OF NX-1607, A FIRST-IN-CLASS ORAL CBL-B INHIBITOR, IN PATIENTS WITH ADVANCED MALIGNANCIES INCLUDING RICHTER TRANSFORMATION DLBCL. Hemasphere. 2022 Jun 23;6(Suppl ):1970-1971.

CAS Number: 2573775-59-2

Molecular Weight: 537.62

Research Area: Cancer; Inflammation/Immunology

Target: E1/E2/E3 Enzyme

• SKU: MEXHY-141432G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-141432G-0
• Package Unit: Get quote
• Quantity Unit: STK