PQA-18, CAS 1604678-82-1

Shelf life (days): 1460.0

Formulation: A powder

Formal Name: 4,8-bis[(3-methyl-2-buten-1-yl)oxy]-2-quinolinecarboxylic acid, 3-methyl-2-buten-1-yl ester

Purity: ≥98%

Formula Markup: C25H31NO4

Formula Weight: 409.51798

CAS Number: 1604678-82-1

Notes: A PAK2 inhibitor (IC50 = 10 nM) and an immunosuppressant; inhibits concanavalin A-induced production of IL-2 in Jurkat T cells (IC50 = 400 nM); decreases disease severity, serum IgE levels, and skin thickness in the NC/Nga mouse model of atopic dermatitis when applied topically at 0.1%; reduces cutaneous nerve fiber density in NC/Nga mice when applied topically at 0.05%; increases graft survival rate in a rat model of small intestine transplant at 4 mg/kg

• SKU: CAY42351-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42351-5
• Package Unit: 5 mg
• Quantity Unit: STK